| # | Player | Team | Games | Q4 rece yds | Per game | Best Q4 |
|---|---|---|---|---|---|---|
| 1 | Ja'Marr Chase | CIN | 16 | 480 | 30.0 | 79 vs DET (wk 5) |
| 2 | George Pickens | DAL | 17 | 426 | 25.1 | 67 vs PHI (wk 12) |
| 3 | Chris Olave | NO | 16 | 407 | 25.4 | 78 vs CAR (wk 15) |
| 4 | Jaxon Smith-Njigba | SEA | 17 | 396 | 23.3 | 69 @ ARI (wk 4) |
| 5 | Zay Flowers | BAL | 17 | 357 | 21.0 | 129 @ PIT (wk 18) |
| 6 | Christian McCaffrey | SF | 17 | 348 | 20.5 | 49 vs JAX (wk 4) |
| 7 | A.J. Brown | PHI | 15 | 339 | 22.6 | 84 @ MIN (wk 7) |
| 8 | Amon-Ra St. Brown | DET | 17 | 333 | 19.6 | 53 vs NYG (wk 12) |
| 9 | Puka Nacua | LA | 16 | 320 | 20.0 | 54 vs HOU (wk 1) |
| 10 | Courtland Sutton | DEN | 17 | 312 | 18.4 | 76 @ PHI (wk 5) |
| 11 | Jameson Williams | DET | 17 | 305 | 17.9 | 60 vs GB (wk 13) |
| 12 | Colston Loveland | CHI | 16 | 281 | 17.6 | 58 @ CIN (wk 9) |
| 13 | Jordan Addison | MIN | 14 | 278 | 19.9 | 87 @ PIT (wk 4) |
| 14 | Jaylen Waddle | MIA | 16 | 266 | 16.6 | 63 @ CAR (wk 5) |
| 15 | Tre Tucker | LV | 17 | 266 | 15.6 | 98 @ WAS (wk 3) |
| 16 | Pat Freiermuth | PIT | 15 | 263 | 17.5 | 92 @ CIN (wk 7) |
| 17 | Juwan Johnson | NO | 17 | 258 | 15.2 | 62 @ TEN (wk 17) |
| 18 | Trey McBride | ARI | 17 | 256 | 15.1 | 45 @ CIN (wk 17) |
| 19 | Harold Fannin Jr. | CLE | 16 | 251 | 15.7 | 56 @ PIT (wk 6) |
| 20 | Michael Wilson | ARI | 17 | 247 | 14.5 | 57 vs LA (wk 14) |
| 21 | Rashid Shaheed | SEA | 18 | 245 | 13.6 | 49 @ LA (wk 9) |
| 22 | Tetairoa McMillan | CAR | 17 | 245 | 14.4 | 49 @ ATL (wk 11) |
| 23 | Nico Collins | HOU | 15 | 244 | 16.3 | 76 @ JAX (wk 3) |
| 24 | Tee Higgins | CIN | 15 | 240 | 16.0 | 56 vs CHI (wk 9) |
| 25 | Emeka Egbuka | TB | 17 | 238 | 14.0 | 40 @ CAR (wk 16) |
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