Matthew Stafford vs San Francisco 49ers — Passing Stats, Quarter by Quarter
Matthew Stafford has averaged 257.7 passing yards per game against the San Francisco 49ers across 3 meetings in our data — best game 333 yards (2025 week 5). His quarter-by-quarter profile vs SF and every meeting's log are below.
Per-quarter averages vs SF
| Q1 | Q2 | Q3 | Q4 |
|---|
| 45.3 | 56.3 | 51.0 | 105.0 |
Every meeting
| Game | Site | Q1 | Q2 | Q3 |
Q4 | Total |
|---|
| 2025 wk 10 | @ SF | 120 | 53 | 23 | 84 | 280 |
| 2025 wk 5 | vs SF | 5 | 104 | 86 | 138 | 333 |
| 2024 wk 15 | @ SF | 11 | 12 | 44 | 93 | 160 |
FAQ
How does Matthew Stafford perform against the San Francisco 49ers?
257.7 passing yards per game across 3 meetings, with a best of 333.
What is Matthew Stafford's best game against SF?
333 passing yards in week 5 of 2025.
Weekly