| Final | Line | ATS | Total |
|---|---|---|---|
| THURSDAY · SEP 11 | |||
| WAS 18 @ GB 27 | GB -3.5 | GB covered | Under 48.5 |
| SUNDAY · SEP 14 | |||
| CLE 17 @ BAL 41 | BAL -12.5 | BAL covered | Over 46.5 |
| JAX 27 @ CIN 31 | CIN -3.5 | CIN covered | Over 49.5 |
| NYG 37 @ DAL 40 | DAL -4.5 | NYG covered | Over 44.5 |
| CHI 21 @ DET 52 | DET -6 | DET covered | Over 46.5 |
| NE 33 @ MIA 27 | MIA -1.5 | NE covered — outright upset | Over 43.5 |
| SF 26 @ NO 21 | SF -3 | SF covered | Over 40.5 |
| BUF 30 @ NYJ 10 | BUF -6 | BUF covered | Under 47.5 |
| SEA 31 @ PIT 17 | PIT -3.5 | SEA covered — outright upset | Over 40.5 |
| LA 33 @ TEN 19 | LA -5.5 | LA covered | Over 41.5 |
| CAR 22 @ ARI 27 | ARI -7 | CAR covered | Over 45.5 |
| DEN 28 @ IND 29 | DEN -2.5 | IND covered — outright upset | Over 43.5 |
| PHI 20 @ KC 17 | PHI -1.5 | PHI covered | Under 46.5 |
| ATL 22 @ MIN 6 | MIN -3.5 | ATL covered — outright upset | Under 44.5 |
| MONDAY · SEP 15 | |||
| TB 20 @ HOU 19 | HOU -2.5 | TB covered — outright upset | Under 42.5 |
| LAC 20 @ LV 9 | LAC -3.5 | LAC covered | Under 46.5 |
Favorites went 9–7 against the closing spread in week 2 of 2025.
Seattle Seahawks beating Pittsburgh Steelers outright as a +3.5 underdog.
Overs went 10–6 across the week's games.
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