| Final | Line | ATS | Total |
|---|---|---|---|
| THURSDAY · NOV 20 | |||
| BUF 19 @ HOU 23 | BUF -5.5 | HOU covered — outright upset | Under 43.5 |
| SUNDAY · NOV 23 | |||
| NYJ 10 @ BAL 23 | BAL -14 | NYJ covered | Under 44.5 |
| PIT 28 @ CHI 31 | CHI -3 | push | Over 46.5 |
| NE 26 @ CIN 20 | NE -7.5 | CIN covered | Under 50.5 |
| NYG 27 @ DET 34 | DET -14 | NYG covered | Over 50.5 |
| MIN 6 @ GB 23 | GB -6.5 | GB covered | Under 41.5 |
| IND 20 @ KC 23 | KC -3.5 | IND covered | Under 50.5 |
| SEA 30 @ TEN 24 | SEA -12.5 | TEN covered | Over 41.5 |
| JAX 27 @ ARI 24 | JAX -2.5 | JAX covered | Over 47.5 |
| CLE 24 @ LV 10 | LV -3 | CLE covered — outright upset | Under 35.5 |
| PHI 21 @ DAL 24 | PHI -3 | DAL covered — outright upset | Under 47.5 |
| ATL 24 @ NO 10 | NO -1.5 | ATL covered — outright upset | Under 41.5 |
| TB 7 @ LA 34 | LA -7 | LA covered | Under 49.5 |
| MONDAY · NOV 24 | |||
| CAR 9 @ SF 20 | SF -7.5 | SF covered | Under 48.5 |
Favorites went 4–9–1 against the closing spread in week 12 of 2025.
Houston Texans beating Buffalo Bills outright as a +5.5 underdog.
Overs went 4–10 across the week's games.
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