| Final | Line | ATS | Total |
|---|---|---|---|
| THURSDAY · NOV 6 | |||
| LV 7 @ DEN 10 | DEN -9.5 | LV covered | Under 42.5 |
| SUNDAY · NOV 9 | |||
| ATL 25 @ IND 31 | IND -6.5 | ATL covered | Over 48.5 |
| NO 17 @ CAR 7 | CAR -5.5 | NO covered — outright upset | Under 38.5 |
| NYG 20 @ CHI 24 | CHI -4.5 | NYG covered | Under 45.5 |
| JAX 29 @ HOU 36 | JAX -1.5 | HOU covered — outright upset | Over 37.5 |
| BUF 13 @ MIA 30 | BUF -8.5 | MIA covered — outright upset | Under 50.5 |
| BAL 27 @ MIN 19 | BAL -4.5 | BAL covered | Under 48.5 |
| CLE 20 @ NYJ 27 | CLE -1.5 | NYJ covered — outright upset | Over 37.5 |
| NE 28 @ TB 23 | TB -2.5 | NE covered — outright upset | Over 48.5 |
| ARI 22 @ SEA 44 | SEA -7 | SEA covered | Over 44.5 |
| LA 42 @ SF 26 | LA -5.5 | LA covered | Over 49.5 |
| DET 44 @ WAS 22 | DET -8.5 | DET covered | Over 49.5 |
| PIT 10 @ LAC 25 | LAC -3 | LAC covered | Under 45.5 |
| MONDAY · NOV 10 | |||
| PHI 10 @ GB 7 | GB -1.5 | PHI covered — outright upset | Under 45.5 |
Favorites went 5–9 against the closing spread in week 10 of 2025.
Miami Dolphins beating Buffalo Bills outright as a +8.5 underdog.
Overs went 7–7 across the week's games.
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