Patrick Mahomes vs Buffalo Bills — Passing Stats, Quarter by Quarter
Patrick Mahomes has averaged 230.3 passing yards per game against the Buffalo Bills across 3 meetings in our data — best game 250 yards (2025 week 9). His quarter-by-quarter profile vs BUF and every meeting's log are below.
Per-quarter averages vs BUF
| Q1 | Q2 | Q3 | Q4 |
|---|
| 47.3 | 70.7 | 38.7 | 73.7 |
Every meeting
| Game | Site | Q1 | Q2 | Q3 |
Q4 | Total |
|---|
| 2025 wk 9 | @ BUF | 20 | 104 | 66 | 60 | 250 |
| 2024 wk 21 | vs BUF | 61 | 71 | 17 | 96 | 245 |
| 2024 wk 11 | @ BUF | 61 | 37 | 33 | 65 | 196 |
FAQ
How does Patrick Mahomes perform against the Buffalo Bills?
230.3 passing yards per game across 3 meetings, with a best of 250.
What is Patrick Mahomes's best game against BUF?
250 passing yards in week 9 of 2025.
Weekly